Search on: GRAVES DISEASE 
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Descriptor English:   Graves Disease 
Descriptor Spanish:   Enfermedad de Graves 
Descriptor Portuguese:   Doença de Graves 
Synonyms English:   Basedow's Disease
Exophthalmic Goiter
Goiter, Exophthalmic
Graves' Disease  
Tree Number:   C11.675.349.500
C19.874.283.605
C19.874.397.370
C20.111.555
Definition English:   A common form of hyperthyroidism with a diffuse hyperplastic GOITER. It is an autoimmune disorder that produces antibodies against the THYROID STIMULATING HORMONE RECEPTOR. These autoantibodies activate the TSH receptor, thereby stimulating the THYROID GLAND and hypersecretion of THYROID HORMONES. These autoantibodies can also affect the eyes (GRAVES OPHTHALMOPATHY) and the skin (Graves dermopathy). 
Indexing Annotation English:   GRAVES OPHTHALMOPATHY is also available
History Note English:   2006 (1987); use GOITER, EXOPHTHALMIC 1963-1986 
Allowable Qualifiers English:  
BL blood CF cerebrospinal fluid
CI chemically induced CL classification
CO complications CN congenital
DI diagnosis DH diet therapy
DT drug therapy EC economics
EM embryology EN enzymology
EP epidemiology EH ethnology
ET etiology GE genetics
HI history IM immunology
ME metabolism MI microbiology
MO mortality NU nursing
PS parasitology PA pathology
PP physiopathology PC prevention & control
PX psychology RA radiography
RI radionuclide imaging RT radiotherapy
RH rehabilitation SU surgery
TH therapy US ultrasonography
UR urine VE veterinary
VI virology  
Record Number:   28071 
Unique Identifier:   D006111 

Occurrence in VHL: 		 

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